Sanjay Tyagi, Ph.D.

Professor of Medicine   |  Laboratory Website
room W310-E


Ranjeet Kumar, Afsal Kolloli and colleagues describe their single-molecule FISH approach for imaging the architecture of tuberculosis granulomas in rabbits and macaques (  Granulomas are created by immune cells around mycobacteria to limit both bacterial dissemination and inflammation in the lung.  The scientists classified immune cells based on mRNA expressions and mapped their distributions.  This approach paves the way for more comprehensive spatial transcriptomic studies that will produce better understanding of the Tuberculosis disease.