Recent Publications

Yang X, Wedajo W, Yamada Y, Dahlroth SL, Neo JJ, Dick T, Chui WK (2018) 1,3,5-triazaspiro[5.5]undeca-2,4-dienes as selective Mycobacterium tuberculosis dihydrofolate reductase inhibitors with potent whole cell activity. Eur J Med Chem 144: 262-276. PMI: 29274493

Yang X, Wedajo W, Yamada Y, Dahlroth S-L, Neo JJ-L, Dick T, Chui W-K (2018) 1,3,5-triazaspiro[5.5]undeca-2,4-dienes as selective Mycobacterium tuberculosis dihydrofolate reductase inhibitors with potent whole cell activity. European Journal of Medicinal Chemistry. PMI:

Wu ML, Aziz DB, Dartois V, Dick T (2018) NTM drug discovery: status, gaps and the way forward. Drug Discov Today. PMI: 29635026

Valdebenito S, Barreto A, Eugenin EA (2018) The role of connexin and pannexin containing channels in the innate and acquired immune response. Biochim Biophys Acta 1860: 154-165. PMI: 28559189

Tanner AW, Carabetta VJ, Dubnau D (2018) ClpC and MecA, components of a proteolytic machine, prevent Spo0A-P-dependent transcription without degradation. Mol Microbiol. PMI: 29446505

Sarathy JP, Via LE, Weiner D, Blanc L, Boshoff H, Eugenin EA, Barry CE, 3rd, Dartois VA (2018) Extreme Drug Tolerance of Mycobacterium tuberculosis in Caseum. Antimicrob Agents Chemother 62. PMI: 29203492

Qualls ZM, Choudhary A, Honnen W, Prattipati R, Robinson JE, Pinter A (2018) Identification of Novel Structural Determinants in MW965 Env That Regulate the Neutralization Phenotype and Conformational Masking Potential of Primary HIV-1 Isolates. J Virol 92. PMI: 29237828

Otten C, Brilli M, Vollmer W, Viollier PH, Salje J (2018) Peptidoglycan in obligate intracellular bacteria. Mol Microbiol 107: 142-163. PMI: 29178391

Masso-Silva J, Espinosa V, Liu TB, Wang Y, Xue C, Rivera A (2018) The F-Box Protein Fbp1 Shapes the Immunogenic Potential of Cryptococcus neoformans. mBio 9. PMI: 29317510

Luan G, Hong Y, Drlica K, Zhao X (2018) Suppression of reactive-oxygen-species accumulation accounts for paradoxical bacterial survival at high quinolone concentration. . Antimicrob. Agents Chemother 62: (in press). PMI:

Liao G, Wang Y, Liu TB, Kohli G, Qian W, Shor E, Subbian S, Xue C (2018) Role of the inositol pyrophosphate multikinase Kcs1 in Cryptococcus inositol metabolism. Fungal Genet Biol. PMI: 29357302

Khandelwal NK, Chauhan N, Sarkar P, Esquivel BD, Coccetti P, Singh A, Coste AT, Gupta M, Sanglard D, White TC, Chauvel M, d’Enfert C, Chattopadhyay A, Gaur NA, Mondal AK, Prasad R (2018) Azole resistance in a Candida albicans mutant lacking the ABC transporter CDR6/ROA1 depends on TOR signaling. J Biol Chem 293: 412-432. PMI: 29158264

Joon S, Ragunathan P, Sundararaman L, Nartey W, Kundu S, Manimekalai MSS, Bogdanovic N, Dick T, Gruber G (2018) The NMR solution structure of Mycobacterium tuberculosis F-ATP synthase subunit epsilon provides new insight into energy coupling inside the rotary engine. FEBS J. PMI: 29360236

Choudhary A, Patel D, Honnen W, Lai Z, Prattipati R, Hsueh Y-C, Gennaro ML, Lardizabal A, Joe M, Bai Y, Spencer J, Lowary TL, Pinter A (2018) Novel human monoclonal antibodies with distinct epitope specificities help characterize the antigenic diversity of lipoarabinomannan (LAM), the major surface glycolipid of Mycobacterium tuberculosis. Journal of immunology In press.: PMI:

Chen C, Gardete S, Jansen RS, Shetty A, Dick T, Rhee KY, Dartois V (2018) Verapamil targets membrane energetics in Mycobacterium tuberculosis. Antimicrob Agents Chemother. PMI: 29463541

Batty EM, Chaemchuen S, Blacksell S, Richards AL, Paris D, Bowden R, Chan C, Lachumanan R, Day N, Donnelly P, Chen S, Salje J (2018) Long-read whole genome sequencing and comparative analysis of six strains of the human pathogen Orientia tsutsugamushi. PLoS Negl Trop Dis 12: e0006566. PMI: 29874223

Ayyappan JP, Vinnard C, Subbian S, Nagajyothi JF (2018) Effect of Mycobacterium tuberculosis infection on adipocyte physiology. Microbes Infect 20: 81-88. PMI: 29109018